Fig. 5.
Quantitative analysis for the numbers of blood and lymphatic vessels in the diabetic mouse kidneys. (A) Number of PECAM-1-stained blood vessels in the ICR-STZ and KK/Ta-HF mouse kidneys. There were no statistically significant differences in the total numbers of renal blood vessels between the ICR control and ICR-STZ mice, or between the KK/Ta control and KK/Ta-HF mice. Data are expressed as means±SD. (B) Number of podoplanin-stained lymphatic vessels in the ICR-STZ mouse kidneys. There were statistically significant differences in the total numbers of renal lymphatic vessels and in the numbers with diameters (d) of 50–100 µm between the ICR-STZ and ICR control mice. There were no statistically significant differences in the numbers of renal lymphatic vessels with diameters under 50 µm or over 100 µm between the ICR-STZ and ICR control mice. Data are expressed as means±SD. *Significantly different (p<0.01). (C) Number of podoplanin-stained lymphatic vessels in the KK/Ta-HF mouse kidneys. There were statistically significant differences in the total numbers of renal lymphatic vessels and in the numbers with diameters (d) under 50 µm between the KK/Ta-HF and KK/Ta control mice. There were no statistically significant differences in the numbers of renal lymphatic vessels with diameters of 50–100 µm or over 100 µm between the KK/Ta-HF and KK/Ta control mice. Data are expressed as means±SD. *Significantly different (p<0.01).