Table 3.
Association Between Postdiagnostic Alcohol Consumption and Death From Breast Cancer, Cardiovascular Disease, or Any Cause
| Postdiagnostic Alcohol Consumption (drinks/wk) | At Risk |
Cause of Death |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Breast Cancer |
Cardiovascular Disease |
Any Cause |
|||||||||
| No. | % | No. of Deaths | HR | 95% CI | No. of Deaths | HR | 95% CI | No. of Deaths | HR | 95% CI | |
| Total | |||||||||||
| 0 | 1,140 | 23 | 69 | 1 | Reference | 97 | 1 | Reference | 326 | 1 | Reference |
| 1-2 | 2,232 | 46 | 122 | 0.88 | 0.61 to 1.27 | 125 | 1.00 | 0.72 to 1.40 | 467 | 0.89 | 0.75 to 1.06 |
| 3-6 | 790 | 16 | 39 | 0.80 | 0.49 to 1.32 | 28 | 0.61 | 0.37 to 1.03 | 141 | 0.77 | 0.60 to 0.98 |
| 7-9 | 305 | 6 | 21 | 1.01 | 0.55 to 1.87 | 11 | 0.50 | 0.24 to 1.03 | 57 | 0.63 | 0.45 to 0.88 |
| ≥ 10 | 414 | 9 | 25 | 0.83 | 0.45 to 1.54 | 15 | 0.47 | 0.24 to 0.91 | 78 | 0.64 | 0.47 to 0.88 |
| Wine | |||||||||||
| 0 | 1,614 | 33 | 100 | 1 | Reference | 125 | 1 | Reference | 452 | 1 | Reference |
| 1-2 | 2,451 | 50 | 128 | 1.00 | 0.70 to 1.42 | 118 | 1.07 | 0.77 to 1.49 | 483 | 0.90 | 0.76 to 1.07 |
| 3-6 | 534 | 11 | 27 | 1.00 | 0.58 to 1.72 | 23 | 1.22 | 0.67 to 2.20 | 84 | 0.76 | 0.57 to 1.03 |
| ≥ 7 | 282 | 6 | 21 | 1.45 | 0.77 to 2.73 | 10 | 0.81 | 0.36 to 1.82 | 50 | 0.73 | 0.51 to 1.05 |
| Beer | |||||||||||
| 0 | 2,830 | 58 | 157 | 1 | Reference | 195 | 1 | Reference | 696 | 1 | Reference |
| 1-2 | 1,731 | 36 | 102 | 1.26 | 0.88 to 1.79 | 74 | 0.85 | 0.58 to 1.24 | 322 | 1.02 | 0.85 to 1.23 |
| 3-6 | 215 | 4 | 10 | 1.04 | 0.49 to 2.22 | 5 | 0.68 | 0.25 to 1.82 | 32 | 1.04 | 0.69 to 1.57 |
| ≥ 7 | 105 | 2 | 7 | 0.94 | 0.37 to 2.39 | 2 | 0.44 | 0.10 to 2.06 | 19 | 0.91 | 0.53 to 1.57 |
| Spirits | |||||||||||
| 0 | 2,406 | 49 | 146 | 1 | Reference | 168 | 1 | Reference | 604 | 1 | Reference |
| 1-2 | 1,826 | 37 | 94 | 0.74 | 0.53 to 1.03 | 78 | 0.78 | 0.54 to 1.11 | 327 | 0.84 | 0.70 to 1.00 |
| 3-6 | 394 | 8 | 20 | 0.78 | 0.45 to 1.36 | 17 | 0.65 | 0.35 to 1.21 | 79 | 0.86 | 0.65 to 1.14 |
| ≥ 7 | 255 | 5 | 16 | 0.83 | 0.43 to 1.62 | 13 | 0.51 | 0.25 to 1.05 | 59 | 0.69 | 0.49 to 0.98 |
NOTE. HR adjusted for prediagnostic alcohol consumption, age at diagnosis, stage of disease at diagnosis, state of residence at diagnosis, study phase, family history of breast cancer, age at first birth, menopausal status, hormone therapy use, body mass index, weight change, smoking status, education, and mammography.
Abbreviation: HR, hazard ratio.