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. 2013 Apr 8;31(16):1939–1946. doi: 10.1200/JCO.2012.46.5765

Table 3.

Association Between Postdiagnostic Alcohol Consumption and Death From Breast Cancer, Cardiovascular Disease, or Any Cause

Postdiagnostic Alcohol Consumption (drinks/wk) At Risk
Cause of Death
Breast Cancer
Cardiovascular Disease
Any Cause
No. % No. of Deaths HR 95% CI No. of Deaths HR 95% CI No. of Deaths HR 95% CI
Total
    0 1,140 23 69 1 Reference 97 1 Reference 326 1 Reference
    1-2 2,232 46 122 0.88 0.61 to 1.27 125 1.00 0.72 to 1.40 467 0.89 0.75 to 1.06
    3-6 790 16 39 0.80 0.49 to 1.32 28 0.61 0.37 to 1.03 141 0.77 0.60 to 0.98
    7-9 305 6 21 1.01 0.55 to 1.87 11 0.50 0.24 to 1.03 57 0.63 0.45 to 0.88
    ≥ 10 414 9 25 0.83 0.45 to 1.54 15 0.47 0.24 to 0.91 78 0.64 0.47 to 0.88
Wine
    0 1,614 33 100 1 Reference 125 1 Reference 452 1 Reference
    1-2 2,451 50 128 1.00 0.70 to 1.42 118 1.07 0.77 to 1.49 483 0.90 0.76 to 1.07
    3-6 534 11 27 1.00 0.58 to 1.72 23 1.22 0.67 to 2.20 84 0.76 0.57 to 1.03
    ≥ 7 282 6 21 1.45 0.77 to 2.73 10 0.81 0.36 to 1.82 50 0.73 0.51 to 1.05
Beer
    0 2,830 58 157 1 Reference 195 1 Reference 696 1 Reference
    1-2 1,731 36 102 1.26 0.88 to 1.79 74 0.85 0.58 to 1.24 322 1.02 0.85 to 1.23
    3-6 215 4 10 1.04 0.49 to 2.22 5 0.68 0.25 to 1.82 32 1.04 0.69 to 1.57
    ≥ 7 105 2 7 0.94 0.37 to 2.39 2 0.44 0.10 to 2.06 19 0.91 0.53 to 1.57
Spirits
    0 2,406 49 146 1 Reference 168 1 Reference 604 1 Reference
    1-2 1,826 37 94 0.74 0.53 to 1.03 78 0.78 0.54 to 1.11 327 0.84 0.70 to 1.00
    3-6 394 8 20 0.78 0.45 to 1.36 17 0.65 0.35 to 1.21 79 0.86 0.65 to 1.14
    ≥ 7 255 5 16 0.83 0.43 to 1.62 13 0.51 0.25 to 1.05 59 0.69 0.49 to 0.98

NOTE. HR adjusted for prediagnostic alcohol consumption, age at diagnosis, stage of disease at diagnosis, state of residence at diagnosis, study phase, family history of breast cancer, age at first birth, menopausal status, hormone therapy use, body mass index, weight change, smoking status, education, and mammography.

Abbreviation: HR, hazard ratio.