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. 2013 Mar 21;5(1):e4. doi: 10.4081/ni.2013.e4

Figure 1.

Figure 1

Immunohistochemical stainings of specimen E582: Haematoxylin & Eosin staining (A) shows densely packed lymphoid tumor cells, which are positive for CD20 (B). Reactive CD3 positive T cells (C) and CD68 positive microglial cells (D) are found within the tumor mass. CD20 positive tumor cells show extensive expression of BAFF (E) and weak to moderate expression of BAFF-R (G), BCMA (H) and TACI (I). No expression of APRIL (F) was found in this specimen. Tonsil tissue served as positive control of anti-BAFF staining (J). Validation of anti-BAFF staining using a second antibody in tumor specimen E236 (K). Cerebellar tissue was used as positive control of anti-APRIL staining (L). Original magnification x200 (K, L), x400 (A–J).