Appendix Table 1.

Parameter estimates for paternal age categories from sensitivity analyses using different offset terms for the Bernoulli outcome.

Paternal age Offset	<20	20–24	25–29	30–34	35–39	40–44	45–49	50–54	55–59	>59
1	0.27*	0.16*	0.00	Ref.	0.07*	0.13*	0.16*	0.22*	0.33*	0.59*
Time at risk	0.22*	0.14*	0.02	Ref.	0.03	0.08*	0.10*	0.20*	0.31*	0.59*
Empirical/incidences	0.23*	0.15*	0.01	Ref.	0.04*	0.09*	0.12*	0.20*	0.31*	0.58*
Birth year
1 + q1*(time at risk)	0.26*	0.16*	0.02	Ref.	0.05*	0.11*	0.14*	0.22*	0.33*	0.60*
1	0.26*	0.16*	0.02	Ref.	0.05*	0.11*	0.14*	0.22*	0.33*	0.60*
Time at risk	0.26*	0.16*	0.02	Ref.	0.05*	0.11*	0.14*	0.22*	0.32*	0.60*
Empirical/incidences	0.26*	0.16*	0.02	Ref.	0.05*	0.11*	0.14*	0.22*	0.32*	0.60*

Note: GLM analyses of Bernoulli outcome, adjusted for covariates and using different offsets.