Table 4.

Cost and effects of standard methadone maintenance treatment vs disulfiram enhanced methadone maintenance

Costs	Cost scenario 1 study condition	Cost scenario 2 real world
Cost of standard methadone maintenance alone	$1,015.34	$732.07
Incremental cost of adding disulfiram	$54.89	$338.16
Improvements in Days of Cocaine Use in the last 30 days		Adjusted for 12 weeks*
Effect of standard methadone maintenance alone	10.06	30.18
Incremental effect of adding disulfiram	4.63	13.89
Improvements in Days of Grams of Cocaine Used during last week		Adjusted for 12 weeks**
Effect of standard methadone maintenance alone	1.05	12.6
Incremental effect of adding disulfiram	1.52	18.24

Source: Petrakis et al. (2001) and our own.

^*Adjusted effectiveness multiplies by 3 the effectiveness in terms of days of cocaine used during the last month, to obtain the effectiveness attributed to 3 months of treatment. This assumes that the reduction is stable over treatment and it is therefore possibly an upper bound of the effectiveness.

^**Adjusted effectiveness multiplies by 12 the effectiveness in terms of grams of cocaine used during the last week, to obtain the effectiveness attributable to 12 weeks of treatment. This assumes that the reduction is stable over treatment and it is therefore possibly an upper bound of the effectiveness.