Table 4.

Intakes of dairy protein, total dairy and milk during adolescence and relative risk (95% confidence interval) of proliferative BBD in NHSII

Exposures	Level of intake					P trend	Per 1 serving/week
Dairy protein
Intake (g/day)*	13	19	24	31	40
No. of BBD cases§/pys¶	137/51,792	137/52,144	123/51,833	152/51,869	133/52,190
Multivariate RR (95% CI)†	1.00 (ref)	1.01 (0.80, 1.29)	0.92 (0.72, 1.17)	1.13 (0.89, 1.43)	0.99 (0.78, 1.27)	0.77
Total dairya
Intake (servings/day)	<1	1–<2	2–<3	3–<4	≥ 4
No. of BBD cases§/pys¶	75/27,810	172/67,998	150/52,146	166/64,101	119/47,773
Multivariate RR (95% CI)†	1.00 (ref)	0.98 (0.74, 1.30)	1.12 (0.83, 1.50)	0.99 (0.74, 1.33)	0.99 (0.71, 1.37)	0.87	1.00 (0.94, 1.06)
Total milkb
Intake (servings/day)	<1	1–<2	2–<3	≥ 3
No. of BBD cases§/pys¶	258/96,333	126/54,651	256/92,765	42/16,079
Multivariate RR (95% CI)†	1.00 (ref)	0.87 (0.70, 1.08)	1.02 (0.85, 1.23)	0.95 (0.67, 1.33)		0.78	1.00 (0.94, 1.07)
Additional adjustment for vitamin D†	1.00 (ref)	0.93 (0.74, 1.18)	1.33 (1.01, 1.73)	1.41 (0.91, 2.17)		0.03	1.11 (1.01, 1.23)

^*Values for calcium, dairy calcium, and dairy protein are medians of nutrient intakes in each quintile, adjusted for total energy intake using the residual method. Values for non-dairy calcium are medians of raw nutrient values in each quintile.

^§682 cases of proliferative BBD (with or without atypia) were diagnosed during the follow-up period 1991–2001.

^†The multivariate models are adjusted the same way as in Table 2. The age-adjusted results are essentially the same, and only multivariate adjusted results are presented.

^aIncludes milk, yogurt, instant breakfast drink, yogurt, cottage or ricotta cheese, cream cheese, other cheese (including grilled cheese sandwich, cheeseburgers, etc.), sherbet, ice cream, and milkshake or frappe. Butter is not included.

^bIncludes chocolate milk and regular milk.