Figure 1.
1H-magnetic resonance metabolite spectra of tibialis anterior (A,B) and soleus (C,D) muscles obtained at 3.0 T from an obese subject (BMI: 30 kg/m2) using short (A,C) and long echo-times (B,D). Both short and long echo-time spectra demonstrate excellent separation of IMCL and EMCL methylene lipid peaks with increased SNR of short echo-time spectrum. IMCL, intramyocellular lipid methyl (CH3) and methylene (CH2) protons at 0.9 and 1.3 ppm; EMCL, extramyocellular lipid methyl (CH3) and methylene (CH2) protons at 1.1 and 1.5 ppm; Cr3, creatine CH3 resonances; TMA, trimethylammonium containing compounds at 3.2 ppm; H2O, residual water signal.