Figure 11.

Western blot analysis on effect of ZER-HPβCD inclusion complex on the levels of apoptosis regulatory proteins in HepG2 cells. Bax was upregulated while Bcl-2 in contrast downregulated in a time-dependent manner. Hsp-70 was also found to be depleted as time increases. The blot densities are expressed as folds of control. Detection of proteins was done by specific antibodies with β-actin as a loading control. Data are mean ± SD (n = 3). *P < 0.05 versus control.