Skip to main content
. Author manuscript; available in PMC: 2013 May 23.
Published in final edited form as: N Engl J Med. 2012 Jul 26;367(4):299–308. doi: 10.1056/NEJMoa1201161

Table 3.

Resource Utilization, Radiation Exposure, and Costs of Care.*

Variable Index Visit Index Plus Follow-up Visit
CCTA (N = 501) Standard Evaluation (N = 499) P Value CCTA (N = 501) Standard Evaluation (N = 499) P Value
Diagnostic testing — no. of patients (%) <0.001 <0.001
 No testing 9 (2) 109 (22) 9 (2) 89 (18)
 1 test 376 (75) 337 (68) 359 (72) 350 (70)
 ≥2 tests 116 (23) 53 (11) 133 (27) 60 (12)
Functional testing — no. (%)§ <0.001 <0.001
 SPECT 50 (10) 124 (25) 58 (12) 133 (27)
 Stress echocardiography 20 (4) 102 (20) 20 (4) 102 (20)
 ETT 12 (2) 147 (29) 22 (4) 162 (32)
Invasive coronary angiography — no. (%) 54 (11) 36 (7) 0.06 59 (12) 40 (8) 0.06
Intervention — no. (%)
 PCI 24 (5) 14 (3) 0.14 27 (5) 17 (3) 0.16
 CABG 5 (1) 4 (1) 0.99 5 (1) 4 (1) 0.99
Cumulative radiation exposure — mSv/patient 13.9±10.4 4.7±8.4 <0.001 14.3±10.9 5.3±9.6 <0.001
Costs of care — U.S. dollars <0.001
 Emergency department
  Mean 2,101±1,070 2,566±1,323
  Median 1,770 2,293
 Interquartile range 1,435–2,161 1,592–3,583
 Hospital 0.19
  Mean 1,925±6,697 1,308±5,333
 Total 0.75 0.65
  Mean 4,026±6,792 3,874±5,298 4,289±7,110 4,060±5,452
  Median 1,937 2,742 1,946 2,809
  Interquartile range 1,504–4,057 1,755–3,832 1,514–4,164 1,822–4,060
*

Plus–minus values are means ±SD. Percentages may not sum to 100 because of rounding. CABG denotes coronary-artery bypass grafting, ETT exercise treadmill testing, PCI percutaneous coronary intervention, and SPECT single-photon-emission computed tomography.

Diagnostic testing included CCTA, ETT, SPECT, stress echocardiography, and invasive coronary angiography.

Serial measurement of biomarkers and electrocardiographic testing were not considered as diagnostic tests in this table.

§

At the index visit, functional testing was the second test in the CCTA group and the first test in the standard-evaluation group.

Radiation exposure included exposure from CCTA, SPECT, and invasive coronary angiography.

Costs included those for patients discharged directly from the emergency department and those discharged from an observation unit.