Fig. 2.

ATRA reduced presence of MDSC in patients with SCLC. Peripheral blood of patients was evaluated before and 1–2 weeks after completion of vaccination. For arm A, blood was collected during enrollment. a Gating strategy used to define cell populations shown in figures (b–e). In all analysis, doublets and dead cells were excluded from the calculation. For gating, matched isotypes controls were used. b–e Cell populations indicated on the graphs were analyzed among live PBMC. Values for individual patients are shown. p values for differences between pre- and post-treatment samples are shown