Table 1.

Summary of studies comparing IFN levels between atopic asthmatics and healthy controls.

IFN	Virus	mRNA / Gene	Protein Release	Decrease in asthmatics?	Reference
Epithelial Cells
IFN-β	HRV-1 b, 16	X		yes	[46] [*]
IFN-β	HRV-1 b, 16		X	ND	[46] [*]
IFN-β	HRV-1a	X		no	[48]
IFN-β	HRV-16	X		no	[49]
IFN-β	HRV-16	X	X	yes	[44]
IFN-β	HRV-16		X	yes	[52] [*]
IFN-λ	HRV-1b, 16		X	ND	[46] [*]
IFN-λ	HRV-16		X	yes	[42]
IFN-λ IFN-λ IFN-λ1	HRV-1b		X	yes	[45]
	HRV-16		X	yes	[52] [*]
	HRV-1b, 16	X		yes	[46] [*]
IFN-λ1	HRV-16	X		yes	[42]
IFN-λ2	HRV-1a	X		no	[48]
IFN-λ2/3	HRV-1b, 16	X		yes	[46] [*]
IFN-λ2/3	HRV-16	X		yes	[42]
Blood Cells / Serum
IFN-α	HRV-16		X	yes [**]	[39] [*]
IFN-α	influenza A		X	yes	[38]
IFN-α (+α2)	HRV-16		X	no	[47]
IFN-β	HRV-16		X	no	[47]
IFN-γ	HRV-16		X	yes	[43]
IFN-λ1	HRV-16 uninfected uninfected		X	yes [**]	[39] [*]
IFN-λ1			X	no	[51]
IFN-λ2/3			X	no	[51]
Nasal and Bronchial Lavage / Sputum
IFN-α2 IFN-α (+α2)	HRV-16		X	no	[30]
	HRV-16		X	yes	[47]
IFN-β	HRV-16		X	yes	[47]
IFN-γ	HRV-16		X	no	[30]
IFN-λ IFN-λ1 IFN-λ2/3	HRV-16 uninfected uninfected	X X	X	yes no no	[42] [50] [50]

ND= not detected,

^[*]Pediatric Study;

^[**]need FcepsilonR1 cross-link to see differences