Figure 1.

Relationship of effect size with degree of support from published guidelines for knee osteoarthritis (OA) treatments. Green shading represents characteristics of an ideal OA treatment, with moderate to large effect size and support from most (>75%) knee OA treatment guidelines. Red shading represents characteristics of an unsatisfactory OA treatment, with trivial to small effect size and support from few (<25%) knee OA treatment guidelines. Yellow shading represents characteristics of equivocal OA treatments, with effect size and knee OA treatment guideline support data not included in categories above. *Effect size not available.