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. 2013 Apr 23;80(17):1598–1605. doi: 10.1212/WNL.0b013e31828f183f

Figure 2. Screen view of CSF analysis utilizing the CellTracks Analyzer II system.

Figure 2

The first 3 rows represent examples of circulating tumor cells (CTCs). They are identified when all of the following criteria are met: the cell is positive for both the epithelial cell marker (CK-PE) and the nuclear dye (DAPI), negative for the leukocyte marker (CD45/APC), and negative in the blank channel. The cells depicted in the last 2 rows do not meet these criteria and therefore are not considered CTCs. CK-PE = cytokeratin-phycoerythrin (specific for intracellular cytokeratin); DAPI = 4′,6-diamidino-2-phenylindole (specific for cell nucleus); CD45-APC = allophycocyanin (specific for leukocytes).