Table 5.

A review of effectiveness estimates for live vaccines

Author (year of publication)	Study design	Type of vaccine	Control	Age of study population	Overall vaccine effectiveness	Lower confidence interval limit	Upper confidence interval limit
Alexandrova (1986)	RCT	Live	Placebo	3-15 years	0.55	0.51	0.60
Khan (1996)	RCT	Live	Placebo	9-12 years	0.47	0.35	0.61
Rudenko (1993)	RCT	Live	Placebo	7-14 years	Year 1: 0.48 Year 2: 0.41	0.22 0.14	0.58 0.54
Rudenko (1996)	RCT	Live	No intervention	3-15 years	Year 1: 0.36 Year 2: 0.48	0.33 0.45	0.39 0.50
Gaglani (2004)	Cohort study	Live	No intervention	1.5-18 years	Year 1: 0.22 Year 2: 0.21	0.11 0.10	0.32 0.31
Halloran (2003)	Cohort study	Live	No intervention	1.5-18 years	0.18	0.11	0.24
Piedra (2005)	Cohort study	Live	Placebo	1.5-5 years	0.07	0.05	0.09
Piedra (2007)	Cohort study	Live	No intervention	5-18 years	0.42	0.35	0.50