Figure 2. Survivin expression is decreased in PAK1^−/− KO islets. Islets were isolated from PAK1^−/− KO and wild type (WT) littermate mice and homogenized. Proteins were resolved by 12% SDS-PAGE for immunoblotting with antibodies as indicated. Data represent the average ± SE for 3 pairs of mice; *p < 0.05, vs. WT.