Table 4.
Predictive value of HIV clinical indicator conditions in the THIN modela
| Indicator condition | Odds ratio | Standard error | z | P-value | 95% CI | |
|---|---|---|---|---|---|---|
| Statistically significant conditions | ||||||
| Bacterial pneumonia | 47.7 | 52.0 | 3.54 | <0.001 | 5.6 | 404.2 |
| Oral candidiasis | 29.4 | 21.8 | 4.57 | <0.001 | 6.9 | 125.5 |
| Herpes zoster | 25.4 | 14.2 | 5.76 | <0.001 | 8.4 | 76.1 |
| Weight loss | 13.4 | 6.7 | 5.15 | <0.001 | 5.0 | 36.0 |
| Non-Hodgkin’s lymphoma | 12.6 | 15.0 | 2.13 | 0.033 | 1.2 | 129.8 |
| Lymphadenopathy | 11.3 | 5.3 | 5.15 | <0.001 | 4.5 | 28.3 |
| Sexually transmitted infection | 10.8 | 7.6 | 3.38 | 0.001 | 2.7 | 43.2 |
| Pyrexia of unknown origin | 7.2 | 3.5 | 4.05 | <0.001 | 2.8 | 18.7 |
| Blood dyscrasia | 5.7 | 4.0 | 2.44 | 0.015 | 1.4 | 22.9 |
| Diarrhoea — one consultation only | 3.7 | 0.9 | 5.48 | <0.001 | 2.3 | 6.0 |
| Diarrhoea — two consultations | 4.4 | 2.3 | 2.81 | 0.005 | 1.6 | 12.1 |
|
| ||||||
| Conditions that were not statistically significantb | ||||||
| Parotitis | 8.6 | 11.0 | 1.68 | 0.093 | 0.7 | 106.1 |
| Psoriasis — one consultation only | 2.6 | 1.5 | 1.69 | 0.091 | 0.9 | 7.9 |
| Psoriasis — two consultations | 3.0 | 2.5 | 1.38 | 0.168 | 0.6 | 14.8 |
a
Also included in conditional logistic regression: Townsend deprivation index and proportion of ward that was Asian and/or Asian British (quintiles).
b
These conditions remained in the stepwise regression model, as their significance was below the 0.2 cut-off threshold for inclusion. Other HIV indicator conditions not shown in the table were excluded during the stepwise process.