Table 3.
Stage 1: performance of items and their combinations identified to be significant through use of multiple logistic regression analysis
| Condition at increased risk | Question number or combination | Sensitivity, % (n) | Specificity, % (n) |
|---|---|---|---|
| Diabetes | 3 | 98 (112/114) | 94 (461/493) |
|
| |||
| Heart disease | 2 | 92 (74/80) | 79 (425/536) |
|
| |||
| Breast cancer | 8 | 73 (19/26) | 84 (321/384) |
| 6 | 28 (7/25) | 97 (374/385) | |
| 8 and 6a | 92 (24/26) | 81 (311/384) | |
|
| |||
| Colorectal cancer | 10 | 85 (11/13) | 96 (573/600) |
| 11 | 54 (7/13) | 89 (535/601) | |
| 10 and 11b | 100 (13/13) | 86 (515/599) | |
a
Combination of questions 6 and 8 is significantly more predictive than question 8 (P < 0.001).
b
Combination of questions 10 and 11 is non-significantly more predictive (P = 0.12) and retained for further assessment in stage 2.