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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Breast Cancer Res Treat. 2012 Oct 21;136(2):593–602. doi: 10.1007/s10549-012-2299-7

Table 3.

Interaction between TCF7L2, history of Type 2 diabetes, and breast cancer risk, The Breast Cancer Health Disparities Study

TCF7L2 Genotype Diabetes history
Cases = 399/controls = 508
OR (95 % CI)
No diabetes history
Cases = 2714/controls = 3244
OR (95 % CI)
Pinteraction P(adj)
rs3750804 CC 1.00 1.00 0.0043 0.0086
CT 0.81 (0.61–1.08) 1.09 (0.97–1.21)
TT 2.46 (1.28–4.73) 1.06 (0.85–1.32)
rs3814570 CC 1.00 1.00 0.0099 0.0099
CT/TT 0.76 (0.58–0.99) 1.13 (1.02–1.26)

OR (odds ratios) and 95 % confidence interval (CI) adjusted for age, study, BMI in referent year, and genetic admixture