Table 1.
Variables | Cohort 1: d4T 40mg (n=235) |
Cohort 2: d4T 30mg (n=240) |
P-Value |
---|---|---|---|
Age (mean, SD) | 34 (8.3) | 33 (9.0) | 0.20 |
Female Sex | 169 (71.5%) | 163 (67.2%) | 0.40 |
Nadir CD4 count cells/uL; median (range) | 120 (2–391) | 135 (2–648) | 0.39 |
Log HIV-1Viral Load median copies/ml (range) | 5.1 (2.6 – 6.6) | 5.1 (1.6 – 6.9) | 0.12 |
Weight kg mean (range/SD) | 66.2 (42–111/10.5) | 56.4 (31–84/10.0) | <0.0001 |
BMI kg/m2 (range) | 24.8 (14.5 – 49.3) | 22.8 (12.6 – 42.6) | <0.0001 |
History of TB Treatment | 47 (20.4%) | 64 (26.6%) | 0.13 |
Current TB Treatment | 42 (18.3%) | 95 (39.8%) | <0.0001 |
Highest Grade of PN: | |||
Grade1 | 60 | 20 | |
Grade2 | 82 | 72 | |
Grade3 | 8 | 8 | |
Grade4 | 6 | 1 |