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. 2013 May 23;8(5):e64204. doi: 10.1371/journal.pone.0064204

Figure 1. GBS binding to immobilized human platelets is mediated by glycoprotein Srr1.

Figure 1

(A) Platelet binding by GBS strains COH31 and NCTC 10/84, their Δsrr1 isogenic variants, and the mutant strains complemented in trans with srr1 (pSrr1). (B) GBS binding to human platelets was inhibited by pretreating the monolayers with 100 µg/ml of anti-fibrinogen IgG (Anti-Fg). Normal IgG (IgG) served as a control. (C) Inhibition of binding by recombinant Srr1 binding region (Srr1-BR). Levels of binding were calculated as relative to the WT strains (mean ± SD). Values shown represent the means (± S.D.) of triplicate measurements. * = P<0.01.