Table 4.
Strain | Expression level (relative amount of AG100; in terms of fold change) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Global activators | Efflux pumps | Porin | |||||||||
soxS | marA | rob | acrA | acrB | acrE | acrD | mdtK | mdfA | tolC | ompF | |
HUE1 | 9.80 | 147.77 | 8.17 | 4.67 | 6.81 | 8.70 | 8.34 | 6.43 | 6.76 | 2.83 | 0.19 |
HUE1A | 4.82 | 80.65 | 4.56 | 2.89 | 3.55 | 4.42 | 3.93 | 3.21 | 3.70 | 2.10 | 0.15 |
HUE1A-Curoqxqnr | 4.99 | 82.95 | 4.81 | 3.04 | 3.61 | 4.33 | 4.06 | 2.99 | 3.77 | 2.21 | 0.15 |
HUE1B-Curoqxqnr | 10.02 | 154.69 | 8.55 | 4.21 | 5.42 | 10.52 | 10.20 | 7.66 | 7.85 | 3.20 | 0.24 |
DH5α | 1.83 | 21.84 | 1.44 | 1.28 | 1.29 | 0.69 | 0.59 | 0.76 | 1.17 | 1.62 | 2.78 |