Table 2.
Effect of acute IP administration of EtOH or acetaldehyde on c-Fos expression in basal ganglia areas of rat brain.
| Brain area | Vehicle | EtOH 0.5 g/kg | EtOH 2.5 g/kg | Acetal 0.1 g/kg | Acetal 0.5 g/kg |
|---|---|---|---|---|---|
| CELL COUNTS (per mm2) ± SEM | |||||
| AcbC | 260.0 ± 66.5 | 486.8 ± 95.7* | 264.8 ± 25.2+ | 693.7 ± 103.8** | 858.4 ± 22.8**## |
| AcbSh | 242.6 ± 51.0 | 349.5 ± 19.7 | 325.6 ± 57.8 | 459.0 ± 55.9** | 633.2 ± 71.3**+## |
| VLS | 229.3 ± 9.6 | 456.5 ± 30.8* | 547.3 ± 95.3** | 594.1 ± 82.6** | 648.6 ± 53.5**# |
| DLS | 258.0 ± 17.2 | 449.3 ± 19.6** | 335.4 ± 19.7 | 569.6 ± 60.1** | 534.0 ± 50.1** |
| DMS | 218.0 ± 29.5 | 462.4 ± 30.2** | 405.8 ± 35.6* | 559.3 ± 91.2** | 562.0 ± 56.9** |
| VP | 151.0 ± 47.0 | 296.8 ± 23.3* | 304.0 ± 58.8* | 328.4 ± 26.1* | 417.5 ± 70.8**## |
Data are the mean number of c-Fos-positive cells (+SEM) per mm2 in the regions listed. (
*
p < 0.05,
**
p < 0.01 different from vehicle for the same brain region,
+
p < 0.05 different from the lower dose of the same drug,
#
p < 0.05,
##
p < 0.01 different from the same dose of EtOH).