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COX-2 and MMPs 2/9 are up-regulated in cutaneous SCC from human. Expression levels for COX-2 and MMPs 2/9 were determined by Western immunoblots with tissue extracts from cutaneous SCCs (T1~T4) and neighboring normal skin (C1~C4) of the same patient for each sample pair. COX-2: cyclooxygenase-2, MMPs 2/9: matrix metalloproteinases-2 and -9, C: control, T: tumor, SCC: squamous cell carcinoma.
