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. 2008 Feb 27;8(3):1366–1399. doi: 10.3390/s8031366

Table 1.

Most important requirements to preserve the bioreceptor functionality

Biorecognition layer (complexity order increases to the bottom) Main requests for functional integrity (the needs usually add up to the bottom)
Single molecule Aptamer / ion carrier (ionophore) Appropriate withholding
Antibody / DNA pH and saline stability
Enzyme / high molecular weigh protein Absence of certain poisoning products (e.g. heavy metals)
Membrane receptor Mechanic protection
Organelle (chloroplast, mitochondrion, etc) Appropriate osmotic pressure, oxygen
Cell Nutrients
Tissue
Organ Undamaged tissue