Table 1.
Thermodynamic parameters for the binding of berenil to calf thymus dsDNA as determined by differential scanning calorimetry analysis
| ΔHcala | ΔHvHb | ΔSTmc | Tmd | <ηmelt>e | RCIf | |
|---|---|---|---|---|---|---|
| dsDNA | 4.76 | 146 | 14.0 | 66.8 | 31 | 6.5 |
| dsDNA + berenil | 1.80 | 452 | 4.9 | 92.8 | 251 | 1.9 |
Calorimetric enthalpy of transition (kcal/mol of base pairs).
Van't Hoff enthalpy of transition (kcal/mol of cooperative melting unit).
Entropy of system at Tm (cal per mol of base pairs/K).
Melting point (°C) at transition when 50% molecules remain folded.
Average number of base pairs in a cooperative melting unit.
Relative cooperative index (°C).