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Kaplan-Meier survival plots for patients with three tumor genotypes in metastatic lung adenocarcinoma treated with EGFR tyrosine kinase inhibitors (TKIs): EGFR mutation (n=41), KRAS mutation (n=8), and WT/WT (n=47). (A) Median OS with EGFR TKI treatment (26.7 months for EGFR mutation vs. 8.2 months for WT/WT vs. 9.2 months for KRAS mutant, p=0.001). (B) Median PFS (12.8 months for EGFR mutation vs. 1.2 months for KRAS mutation vs. 1.9 months for WT/WT, p<0.001).
