Table 3.
Mortality data—randomized controlled trials
| All-cause mortality |
Vascular mortality |
|||||||
|---|---|---|---|---|---|---|---|---|
| Primary author (trial name) | Publication year | Deaths (n) | Patients (n) | Rate per 100 patient-years | Deaths (n) | Patients, (n) | Rate per 100 patient-years | Percentage of all-cause deaths that were vascular |
| Albers13 | 2005 | 123 | 1962 | 3.8 | NR | NR | NR | NR |
| Bousser14 | 2008 | 61 | 2293 | 2.9 | 33 | 2293 | 1.5 | 54.1 |
| Chen11 | 2009 | 10 | 659 | 0.5 | NR | NR | NR | NR |
| Connolly15 | 2006 | 158 | 3371 | 3.8 | 106 | 3371 | 2.5 | 67.1 |
| Connolly16 | 2009 | 487 | 6022 | 4.1 | 317 | 6022 | 2.7 | 65.1 |
| Granger17 | 2011 | 669 | 9081 | 3.9 | 343 | 9081 | 2.0 | 51.3 |
| Hu25 | 2006 | 4 | 335 | 0.8 | NR | NR | NR | NR |
| Lip18 | 2009 | 2 | 318 | 1.4 | NR | NR | NR | NR |
| Mant19 | 2007 | 107 | 488 | 8.0 | 41 | 488 | 3.1 | 38.3 |
| Morocutti12 | 1997 | 32 | 454 | 7.4 | 29 | 454 | 6.7 | 90.6 |
| Patel24 | 2011 | 632 | 7090 | 4.9 | 193 | 7082 | 1.7 | 30.6 |
| Pérez-Gómez23 | 2004 | 43 | 479 | 3.7 | 28 | 479 | 2.4 | 65.1 |
| Petersen9 | 1989 | NR | NR | NR | 3 | 335 | 0.5 | NR |
| SPAF Investigators10 | 1994 | 62 | 555 | 5.6 | 36 | 555 | 3.3 | 58.1 |
| SPAF Investigators21 | 1996 | 35 | 523 | 5.9 | 27 | 523 | 4.6 | 77.1 |
| Olsson22 | 2003 | 79 | 1703 | 3.2 | NR | NR | NR | NR |
NR, not reported.