Table 2.
Baseline GA measure scores among older adults initiating induction chemotherapy for AML (N = 74)
| GA scores | Median (25th, 75th) | % Impaired |
|---|---|---|
| Cognition | ||
| 3MS (range 0-100, impairment < 77) | 85.0 (75.0, 91.0) | 28.8 |
| Psychological function | ||
| CES-D (range 0-60, impairment > 16) | 11.0 (4.0, 21.0) | 39.7 |
| DT (range 0-10, impairment ≥ 4) | 5.0 (2.0, 8.0) | 58.9 |
| PF | ||
| PAT-D* (range 1-5, impairment > 1) at the time of treatment | 1.4 (1.0, 1.8) | 72.4 |
| ADL subscale | 1.0 (1.0, 1.4) | 50.0 |
| IADL subscale | 1.0 (1.0, 1.7) | 40.5 |
| Mobility subscale | 2.0 (1.0, 3.0) | 68.9 |
| PAT-D* 6-mo recall | 1.1 (1.0, 1.3) | |
| ADL subscale | 1.0 (1.0, 1.0) | 23.3 |
| IADL subscale | 1.0 (1.0, 1.0) | 20.6 |
| Mobility subscale | 1.0 (1.0, 1.7) | 41.1 |
| SPPB (range 0-12, impairment < 9) | 8.5 (3.0, 10.0) | 50.0 |
| Grip strength (kg)† | ||
| Male | 38.0 (32.0, 44.0) | |
| Female | 24.0 (22.0, 28.0) | |
| Comorbidity | ||
| HCT-CI (impairment > 1) | 1.0 (0.0, 3.0) | 41.9 |
For 3MS, SPPB, and grip strength, a higher score reflects better function. For CES-D, DT, PAT-D, and HCT-CI, a higher score reflects worse function.
ADL, Activities of Daily Living; DT, Distress Thermometer; HCT-CI, Hematopoietic Stem Cell Transplantation Comorbidity Index; IADL, Instrumental Activities of Daily Living; PAT-D, Pepper Assessment Tool for Disability.
*
Results based on subjects with calculable survey scores (reported in Results section).
†
Scores are based on 67 subjects who performed grip strength.