Fig. 8.

Comparison of the ability of VSDs to report neural activity. (a) Traces illustrate fluorescence signals recorded from slices stained with approximately 1 mM concentrations of each dye. Responses are obtained at similar excitation light intensities (0.6–0.7 mW) and are arranged in decreasing order of ΔF/F response magnitudes. (b) Mean values of ΔF/F signals (n = 20–42) measured for each dye. (c) Mean values of S/N measured for each dye (n = 6–12). Error bars in (b) and (c) indicate ±1 SEM