Figure 8.
nPOPG suppresses lung inflammation elicited by RSV. (A) Lungs from sham-infected (CONL) or RSV-infected mice treated with nPOPG were fixed in 10% buffered formalin, embedded in paraffin, and stained with hematoxylineosin. Lung sections from each animal were evaluated and given a histopathology score. Values shown are the means ± SE. *P = 4.1 × 10−6. (B) Representative micrographs from the CONL- and virus-infected groups treated with 400 μg/mL nPOPG.
Note: The bar inset in the CONL panels corresponds to 200 μm.
Abbreviations: CONL, uninfected control; nPOPG, nanodisc palmitoyl-oleoyl-phosphatidylglycerol; RSV, respiratory syncytial virus; SE, standard errors of the mean.