Table 7.

Comparison between resting and exercising effects and dose 1–2 hours following 0.4 ppm, 2 hr O₃ exposure.

Measurement	Resting exposure	Exercising exposure	Exercise/rest	Reference for exercising exposure
O3minus air
FEV1 % decrement	~2	10.3*	5.0	1
BALF cell 18O	5.6*	28.4*	5.1	1
BAL surfactant 18O	26.4*	51.6*	2.0	1
Nasal lavage 18O	377*	192*	0.5	1
O3/air ratio
BALF cells recovered, % decrement	19*	28*	1.5	1
BALF neutrophils, fold increase	1.52*	7.6*	5.0	1,2
BALF protein, fold increase	0.99	1.9*	2.0	1,2
BALF cell phagocytosis (serum opsonized), % decrement	20*	23	1.2	2
BALF cell phagocytosis (IgG opsonized ), % decrement	1	26*	26	2
BALF cell phagocytosis (unopsonized), % decrement	24	45*	1.9	2
BALF IL6, fold increase	1.1	7.3*	6.9	2
BALF LDH, fold increase	1.2	1.5*	1.3	2
BALF a1-AT, fold increase	1.1	1.7*	1.5	2
BALF C3a fold increase	2.3	1.4	0.6	2

Notes:

^*Significant effect of O₃ compared to respective air exposed.

¹Hatch et al, 1994;

²Devlin et al, 1996.