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. 2013 Apr 5;288(21):14756–14768. doi: 10.1074/jbc.M113.466169

FIGURE 5.

FIGURE 5.

Deletions within the stalk region differentially influence constitutive IL-6R shedding. A and B, HEK293 cells were transfected with the indicated IL-6R constructs. 48 h after transfection medium was replaced with serum-free medium. The amount of constitutive shed IL-6R over a time period of 24 h was determined via ELISA. ELISA data are the mean ± S.D. from three independent experiments.