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Validation of the hnRNP-K-regulated gene targets identified by cDNA array. Gene-specific RT-PCR in control and hnRNP-K-overexpressing cells confirmed the up-regulation of the downstream genes as shown (A). hnRNP-K-overexpressing cells showed higher expression level of MMP-3 and PTGS2 (Western blotting, B), CTGF, and CCK3 (immunostaining, C).
