TABLE 2.
The top seven most down-regulated genes induced by overexpressing hnRNP-K in NIH 3T3 cells
| Gene | Fold change | Biological progress |
|---|---|---|
| Col12a1 | 6.99 | Cell adhesion |
| Prelp | 5.14 | Cell aging |
| Igsf10 | 5.03 | Ossification; protein amino acid phosphorylation; vascular endothelial growth factor receptor signaling pathway |
| Slc47a1 | 4.56 | Multidrug transport; transmembrane transport; transport monomers |
| Il2rg | 3.87 | Positive regulation of B cell differentiation; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T celldifferentiation; positive regulation of T cell differentiation in the thymus |
| Tcn2 | 3.30 | Cobalamin transport; cobalt ion transport; ion transport; transport |
| Kng1 | 2.97 | Blood coagulation; inflammatory response; regulation of blood vessel size; vasodilation |