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. 2013 Apr 5;288(21):15046–15056. doi: 10.1074/jbc.M113.466136

TABLE 2.

The top seven most down-regulated genes induced by overexpressing hnRNP-K in NIH 3T3 cells

Gene Fold change Biological progress
Col12a1 6.99 Cell adhesion
Prelp 5.14 Cell aging
Igsf10 5.03 Ossification; protein amino acid phosphorylation; vascular endothelial growth factor receptor signaling pathway
Slc47a1 4.56 Multidrug transport; transmembrane transport; transport monomers
Il2rg 3.87 Positive regulation of B cell differentiation; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T celldifferentiation; positive regulation of T cell differentiation in the thymus
Tcn2 3.30 Cobalamin transport; cobalt ion transport; ion transport; transport
Kng1 2.97 Blood coagulation; inflammatory response; regulation of blood vessel size; vasodilation