TABLE 3.

Comparison of specific activity between DHS homotetramers and heterotetramers

Data were collected at fixed substrate concentrations (1 mm NAD⁺, 7.5 μm [³H]spermidine, and 10 μm eIF5A). Error represents the mean ± S.D. for six replicates.

	Specific activity
	s−1
Substrate	TbeIF5A	HseIF5A
Enzyme
HsDHS	0.0029 ± 0.0001	0.016 ± 0.0003
TbDHSc	1.8 × 10−6 ± 2 × 10−8	<10−7
TbDHSp	<10−7	<10−7
TbDHSc-TbDHSp	0.0057 ± 0.0001	0.0035 ± 0.0001