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Effects of ozone on methacholine-induced pulmonary mechanics. Total lung resistance, total lung compliance, static compliance, and end tidal volume were evaluated in response to increasing doses of methacholine 24h following exposure of rats to air or ozone. Values were normalized and expressed as percentage change from baseline. Each point is the mean ± SE (n = 6 rats). *Significantly different (p ≤ 0.05) from air-exposed animals.
