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ppk2 deficiency impairs M. tuberculosis growth and survival in J774 macrophages. Growth and survival of the wild type, ppk2::Tn mutant, and ppk2::Tn Comp strain after infection of activated (A) and naive (B) J774 murine macrophages. Values that were significantly different (P < 0.05) are indicated by a bar and asterisk. Three biological replicate samples were used for each strain in each experiment.
