Table 2.
Details of the three DTARs used as interview material
| Galactomannan review | MRI versus CT review | Physical examination review | |
|---|---|---|---|
|
Index test(s) |
Galactomannan sandwich ELISA (Platelia©) |
Diffusion-weighted MRI and CT (for the diagnosis of acute ischemic stroke); MRI (for the diagnosis of acute hemorrhagic stroke) |
A number of physical examination tests such as straight leg raising and crossed straight leg raising tests. |
|
Reference standard |
EORTC/MSG criteria (see review) |
Acute ischemic stroke: a combination of clinical and imaging information supported by clinical or imaging follow-up (CT or MRI) or autopsy; |
Diagnostic imaging or findings at surgery |
| Acute hemorrhagic stroke: a clinical diagnosis supported by CT or autopsy | |||
|
Target condition |
Invasive aspergillosis |
Acute ischemic stroke; acute hemorrhagic stroke |
Radiculopathy due to lower lumbar disc herniation |
| Presentation of the results from meta-analysis | Estimates of sensitivity and specificity (percentages) and false positive and false negative rates (natural frequencies) | Estimates of sensitivity and specificity (percentages) | Estimates of sensitivity and specificity (percentages) |