TABLE 1.

Published series on surgical resection of duodenal adenocarcinoma

Study	Study period	Total no. patients resected	PD, n (%)	5-year survival (%)	Predictors of survival
					Nonpredictors	Univariate	Multivariate
Alwmark et al.11	1958–1973	19	12 (63)	25	–	–	–
Ouriel et al.6	1950–1981	19	11 (58)	30/65a	–	Histologic grade, nodal metastasis	–
Lowell etal.12	1970–1991	17	8 (47)	45	–	First/second portion of duodenum	–
Barnes et al.7	1967–1991	36	27 (75)	54	Nodal metastasis	Stage	–
Delcore et al.13	1960–1990	28	21 (75)	60	–	GI bleeding, symptomatic >4 months, nodal metastasis	–
Rotman et al.14	1978–1988	46	38 (83)	45	Gender, age, weight loss, jaundice, T stage, tumor size, pancreatic invasion nodal metastasis, location of metastatic nodes	–	–
Sexe et al.20	1987–1991	34	31 (91)	23	AJCC stage	–	–
Sohn et al.21	1984–1996	48	35 (73)	53	Nodal metastasis, adjuvant chemoradiation, tumor size, histologic grade	Positive margins, segmental resection, tumor in Third/fourth portion of duodenum	–
Bakaeen et al.15	1976–1996	68	50 (74)	54	Histologic grade, tumor size, location in duodenum, adjuvant chemoradiation	Age, weight loss, T stage, nodal metastasis, AJCC stage	Weight loss, positive margins, nodal metastasis, AJCC stage
Kaklamanos et al.8	1978–1998	37	26 (70)	30/60a	Age, gender, grade, T stage	Nodal metastasis	Nodal metastasis
Ryder et al.9	1957–1998	31	27 (87)	43	Nodal metastases, location in duodenum, type of resection, adjuvant chemoradiation		Tumor size, histologic grade, transmural invasion
Sarela etal.10	1983–2000	72	56 (78)	71	Gender, grade, T stage	Age, nodal metastasis	Age, nodal metastasis
Hurtuk et al.16	1984–2005	35	24 (69)	45	Grade, positive margins, nodal metastasis, venous or perineural invasion	T4, tumor ≤ 3.5 cm	–
Lee et al.19	1995–2007	28	27 (96)	44	Age, gender, weight loss, CA19-9, grade, tumor size	T stage, nodal metastasis, AJCC stage	Nodal metastasis
Han et al.17	1990–2006	22	18 (82)	30	–	Positive margins	–
Struck et al.18	1989–2006	30	25 (83)	33 (3 y)	Positive margins, T stage, adjuvant therapy	–	Nodal metastasis, stage
Current study	1984–2006	112	112 (100)	48	T stage, tumor size	Grade, positive margins, perineural invasion, nodal metastasis, vascular invasion	Nodal metastasis,

PD pancreaticoduodenectomy, GI gastrointestinal

^aAfter segmental resection/pancreaticoduodenectomy