TABLE 3.
Univariate and multivariate proportional hazard model for overall survival after curative resection of duodenal adenocarcinoma (n = 112)
| Characteristic | No. of patients | 5-year overall survival | Univariate analysis
|
Multivariate analysis
|
||
|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | P | |||
| T stage | ||||||
| 1–2 | 19 | 58% | ||||
| 3–4 | 80 | 46% | 1.4 (0.7–2.8) | 0.29 | – | – |
| Missing | 13 | – | – | – | – | – |
| Tumor size | ||||||
| <2 cm | 14 | 44% | ||||
| ≥2 cm | 91 | 49% | 1.2 (0.5–2.6) | 0.64 | – | – |
| Missing | 7 | – | – | – | – | – |
| Lymph node metastasis | ||||||
| N0 | 41 | 68% | Reference | Reference | ||
| N1 | 47 | 58% | 2.1 (1.3–3.8) | 0.03 | 1.9 (1.2–3.3) | 0.02 |
| N2 | 24 | 17% | 4.3 (2.1–9.8) | <0.01 | 3.1 (1.6–5.7) | <0.01 |
| Missing | 0 | – | – | – | – | – |
| Tumor differentiation | ||||||
| Well/moderate | 69 | 58% | ||||
| Poor | 36 | 39% | 2.0 (1.2–3.2) | <0.01 | – | – |
| Missing | 7 | – | – | – | – | – |
| Perineural invasion | ||||||
| No | 49 | 59% | ||||
| Yes | 25 | 44% | 2.2 (1.2–4.0) | <0.01 | – | – |
| Missing | 38 | – | – | – | – | – |
| Vascular invasion | ||||||
| No | 44 | 65% | ||||
| Yes | 25 | 34% | 3.7 (1.9–7.0) | <0.01 | 1.4 (0.9–52.3) | 0.11 |
| Missing | 43 | – | – | – | – | – |
| Margin status | ||||||
| R0 | 107 | 55% | ||||
| R1 | 5 | 0% | 3.3 (1.5–7.2) | <0.01 | 1.7 (0.2–5.5) | 0.59 |
| Missing | 0 | – | – | – | – | – |
| Adjuvant chemoradiation | ||||||
| No | 78 | 48% | ||||
| Yes | 34 | 47% | 1.1 (0.6–1.9) | 0.82 | 1.26 (0.8–2.0) | 0.96 |
| Missing | 0 | – | – | – | – | – |
CI confidence interval