Table 3.

Immunological parameters showing an age-related decline

Immunological parameters	Male (N = 162)				Female (N = 194)				Gender difference
	Slope	Intercept	R	p-value	Slope	Intercept	R	p-value	p-value
(a) T cells※	−33.00	3196	0.187	0.018	−26.57	2628	0.089	0.212	0.049
(b) CD8 + T cells※	−15.94	1315	0.286	<0.001	−13.24	1075	0.305	<0.001	NS
(c) CD8 + CD28+ T cells※	−11.21	863	0.543	<0.001	−8.664	696	0.477	<0.001	0.04
(d) Naïve T cells※	−15.39	1205	0.089	0.261	−10.88	916	0.055	0.447	0.001
(e) T cells proliferative activity	−0.019	2.295	0.315	<0.001	−0.016	2.115	0.224	0.002	NS
(f) T cell proliferation index	−0.056	4.904	0.290	<0.001	−0.043	3.910	0.190	0.008	0.010
(g) T cell immune score	−0.137	19.3	0.261	0.001	−0.106	17.3	0.333	<0.001	0.006
(h) B cells※	−11.04	747	0.167	0.034	−4.307	328	0.105	0.152	0.001

※: Number / mm³. R: Correlation coefficient. NS: not significant.