Table 4.
Immunological parameters showing an age-related increase
| Immunological parameters |
Male (N = 162) |
Female (N = 194) |
Gender difference |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Slope | Intercept | R | p-value | Slope | Intercept | R | p-value | p-value | |
| (a) CD4 + T cells※ |
23.28 |
−313 |
<0.001 |
0.990 |
16.92 |
77 |
0.114 |
0.107 |
0.004 |
| (b) CD4/CD8 ratio |
0.087 |
−2.260 |
0.316 |
<0.001 |
0.064 |
−0.713 |
0.452 |
<0.001 |
0.001 |
| (c) Memory T cells※ |
12.35 |
−141 |
0.114 |
0.153 |
10.11 |
−91 |
0.253 |
<0.001 |
<0.001 |
| (d) CD4 + CD25 + T cells ※ |
1.830 |
−47 |
0.077 |
0.379 |
1.602 |
−33 |
0.100 |
0.233 |
NS |
| (e) NK cells※ | 17.41 | −449 | 0.105 | 0.194 | 11.94 | −186 | 0.268 | <0.001 | 0.001 |
※: Number/mm3. R: Correlation coefficient. NS: not significant.