Table 3. Allelic analysis of SNP rs3825214 association with AF and VT.

Cohort (cases/controls)	Frequency of G allele (cases/controls)	P-obs	P-adj	OR (95% CI)
AF group
Male (424/543)	0.419/0.455	0.117	0.091	0.81 (0.63–1.04)
Female (259/310)	0.407/0.450	0.148	0.143	0.76 (0.53–1.10)
Total AF (692/856)	0.414/0.452	0.036	0.025	0.79 (0.64–0.97)
Lone AF (275/856)	0.376/0.452	0.002	0.001	0.65 (0.50–0.84)
Other AF (417/856)	0.439/0.452	0.546	0.631	1.08 (0.80–1.45)
CAD (175/856)	0.446/0.452	0.927	0.361	0.80 (0.49–1.30)
Hypertension (266/796)	0.417/0.467	0.364	0.001	0.59 (0.43–0.81)
T2DM (45/848)	0.478/0.456	0.683	0.134	2.62 (0.74–9.27)
Stroke (87/856)	0.489/0.452	0.351	0.558	1.25 (0.60–2.62)
VT group
Male (144/543)	0.448/0.455	0.833	0.653	1.10 (0.73–1.66)
Female (91/310)	0.390/0.450	0.152	0.774	1.08 (0.64–1.83)
Total VT (235/856)	0.426/0.452	0.315	0.712	1.06 (0.77–1.47)
AVB (24/856)	0.292/0.452	0.028	0.035	0.49 (0.26–0.95)
BBB (29/856)	0.431/0.452	0.758	0.371	1.55 (0.59–4.03)
Bradycardia (27/856)	0.463/0.452	0.868	0.684	1.25 (0.42–3.71)
ER (12/856)	0.500/0.452	0.636	0.661	1.34 (0.37–4.89)
HCM (26/856)	0.365/0.452	0.219	0.674	1.20 (0.51–2.82)
MVA (61/856)	0.385/0.452	0.155	0.469	1.25 (0.69–2.27)

BBB: bundle branch block; ER: early repolarization; HCM: hypertrophic cardiomyopathy; MVA: malignant ventricular arrhythmia.