Table 2.
Summery of the detection of recombinant hnRNP DL /CNBP and differential recognition of methylated CNBP protein by the anti-Sm positive sera from SLE patients screened in this study
|
SLE patient |
Detection of recombinant |
Differential CNBP methylation |
|||
|---|---|---|---|---|---|
| GST-hnRNP DL | GST-CNBP | (His)6-CNBP | FLAG-CNBP | (His)6-CNBP | |
| X1 |
+ |
+ |
+ |
− |
+ |
| X2 |
+ |
+ |
+ |
− |
− |
| X3 |
+ |
− |
+ |
− |
± |
| X4 |
+ |
− |
+ |
− |
− |
| X5 |
+ |
+ |
+ |
+ |
± |
| X6 |
+ |
+ |
+ |
− |
− |
| X7 |
+ |
− |
+ |
− |
− |
| X8 |
+ |
+ |
+ |
− |
− |
| X9 |
+ |
+ |
+ |
− |
− |
| X10 |
+ |
− |
+ |
− |
− |
| X11 |
+ |
+ |
+ |
− |
± |
| X12 |
+ |
+ |
+ |
− |
+ |
| X13 |
+ |
− |
± |
− |
− |
| X14 |
+ |
− |
± |
− |
− |
| X15 |
+ |
+ |
+ |
− |
− |
| X16 |
+ |
− |
+ |
− |
− |
| X17 |
+ |
+ |
+ |
− |
± |
| X18 |
+ |
+ |
+ |
+ |
± |
| X19 |
+ |
− |
+ |
− |
+ |
| X20 | + | + | ND | − | ND |