Table 3. Characteristics of male subjects grouped by ACE and A3B genotypes.
Mean ± SD (No. of subjects measured) | |||
Characteristic | ACE D/A3B I carriers | others | P-value |
Age (years) | 41.1±11.9 (340) | 41.5±12.4 (343) | 0.692 |
BMI (kg/m2) | 26.2±3.2 (296) | 25.8±3.3 (297) | 0.220 |
Heart rate (beats/min) | 76.7±10.6 (305) | 76.3±10.7 (305) | 0.637 |
Blood pressure (mm Hg) | |||
Systolic | 135.9±18.6 (305) | 133.7±17.9 (305) | 0.201 |
Diastolic | 83.8±11.9 (305) | 83.1±11.4 (305) | 0.490 |
Plasma glucose (mmol/L) | 5.81±1.91 (304) | 5.58±1.14 (312) | 0.629 |
Serum lipid (mmol/L) | |||
Total cholesterol | 4.92±0.87 (304) | 4.83±0.92 (313) | 0.153 |
Triglycerides | 1.94±1.41 (304) | 1.80±1.36 (313) | 0.098 |
HDL-cholesterol | 1.54±0.54 (253) | 1.55±0.57 (261) | 0.943 |
LDL-cholesterol | 3.11±0.81 (253) | 3.05±0.76 (261) | 0.513 |
HDL-C/LDL-C ratio | 0.52±0.21 (253) | 0.53±0.23 (261) | 0.701 |
Renal function indexes | |||
BUN (mmol/L) | 5.27±1.29 (305) | 5.40±1.35 (314) | 0.222 |
Urinary protein | ——a (319) | ——a (328) | 0.956 |
Urinary occult blood | ——a (319) | ——a (328) | 0.155 |
Liver function indexes (U/L) | |||
ALT | 32.9±25.0 (323) | 31.0±19.2 (332) | 0.915 |
γ–GT | 45.2±45.6 (323) | 43.5±43.4 (332) | 0.735 |
AST | 26.0±12.4 (323) | 24.8±9.3 (333) | 0.784 |
Triglycerides | 1.95±1.45 (284) | 1.77±1.36 (291) | 0.103b |
belong to categorical variables.
p-value from analysis of covariance including subjects whose BMI data were available.
Abbreviations: BMI, body mass index; HDL, high density lipoprotein; LDL, low density lipoprotein; BUN, blood urea nitrogen; ALT, alanine aminotransferase; γ–GT, gamma-glutamyl transpeptidase; AST, aspartate aminotransferas.