Table 4. Characteristics of female subjects grouped by ACE and A3B genotypes.
Mean ± SD (No. of subjects measured) | |||
Characteristic | ACE D/A3B I carriers | others | P-value |
Age (years) | 42.2±12.5 (267) | 41.7±12.5 (249) | 0.740 |
BMI (kg/m2) | 23.5±3.4 (231) | 23.4±3.2 (217) | 0.965 |
Heart rate (beats/min) | 80.2±11.7 (245) | 79.5±10.7 (228) | 0.718 |
Blood pressure (mm Hg) | |||
Systolic | 125.9±19.9 (245) | 125.9±19.5 (228) | 0.995 |
Diastolic | 75.8±11.4 (245) | 76.0±12.7 (228) | 0.962 |
Plasma glucose (mmol/L) | 5.24±0.72 (241) | 5.27±0.82 (230) | 0.431 |
Serum lipid (mmol/L) | |||
Total cholesterol | 4.80±0.90 (241) | 4.80±0.91 (226) | 0.825 |
Triglycerides | 1.26±0.86 (241) | 1.25±0.91 (226) | 0.990 |
HDL-cholesterol | 1.88±0.70 (191) | 2.00±0.75 (186) | 0.134 |
LDL-cholesterol | 2.90±0.77 (191) | 2.85±0.76 (186) | 0.522 |
HDL-C/LDL-C ratio | 0.71±0.36 (191) | 0.76±0.40 (186) | 0.181 |
Renal function indexes | |||
BUN (mmol/L) | 4.62±1.29 (239) | 4.53±1.09 (227) | 0.784 |
Urinary protein | ——a (236) | ——a (232) | 0.408 |
Urinary occult blood | ——a (236) | ——a (232) | 0.474 |
Liver function indexes (U/L) | |||
ALT | 22.0±35.3 (248) | 19.1±15.5 (238) | 0.214 |
γ–GT | 21.4±19.1 (248) | 21.8±19.5 (238) | 0.650 |
AST | 22.8±17.1 (248) | 20.8±9.7 (240) | 0.051b |
belong to categorical variables.
Analysis of covariance can not be employed because the data can't be transformed to normality.
Abbreviations: BMI, body mass index; HDL, high density lipoprotein; LDL, low density lipoprotein; BUN, blood urea nitrogen; ALT, alanine aminotransferase; γ–GT, gamma-glutamyl transpeptidase; AST, aspartate aminotransferase.