(a) 2D MEIOSIS pulse sequence for simultaneous acquisition of four experiments: DARR, N(CA)CX, NCO, and CA(N)CO. (b) MEIOSIS pulse sequence with CON and CAN transfers inverted. The phase cycle of 2D MEIOSIS and conventional pulse sequences of Fig. 1S of the supplementary material36 are given by: ϕ1 = (y)4, (−y)4, ϕ2 = (x, x, −x, −x)2, ϕ3 = (y, −y)4, ϕ4 = (y, y, −y, −y)2, and ϕrec = (x, −x, −x, x, −x, x, x, −x). For indirect dimension, states mode acquisition is obtained by alternating the ϕ* between x and y.