Table 4.
GEE parameter estimates for INR predicting Transplantation only
| Parameter | Estimate | Odds Ratio | p-value | 95% Confidence Limits for Odds Ratio | |
|---|---|---|---|---|---|
| Placebo 3-4 | 0.66 | 1.94 | 0.0715 | 0.76 | 4.95 |
| NAC 3-4 | 0.48 | 1.61 | 0.49 | 5.26 | |
| Placebo 1-2 | 1.04 | 2.82 | 1.28 | 6.24 | |
| NAC 1-2* | 0.00 | 1.00 | |||
| Day 1 | 0.15 | 1.16 | 0.0281 | 0.87 | 1.54 |
| Day 2 | 0.26 | 1.30 | 1.00 | 1.68 | |
| Day 3 | 0.26 | 1.30 | 1.06 | 1.58 | |
| Day 4** | 0.00 | 1.00 | |||
| Log10(INR) | 2.13 | 8.38 | 0.0004 | 2.41 | 29.14 |
Using NAC 1-2 as the reference group, all other groups show positive estimate values indicating higher likelihood of transplantation. Day 4 is the reference day that is then compared with the prior 3 days. The effect is greatest on Days 2 and 3 and less so for Day 1 compared to Day 4.
Reference group for Treatment/Coma combination
Reference group for Days 1-3