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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Gut. 2012 Jul 24;62(10):1446–1455. doi: 10.1136/gutjnl-2011-301439

Figure 2.

Figure 2

Immunophenotyping of Mtg16−/− colons reveals increased innate and adaptive immunity. (A) Immunophenotyping using flow cytometry of WT or Mtg16−/− colons (WT (n=6) or Mtg16−/− (n=6) colons). (B) Representative density plots for CD4 IFN-γ-producing cells are shown (cell percentages displayed in corners). (C) Increased IFN-γ production by CD4 cells in Mtg16−/− colons. (D) mRNA expression from Mtg16−/− colons presented as fold change from WT (dashed line, SD shown, ***p<0.001). (E) Multi-analyte profiling using the Luminex platform demonstrating increased IL-17, IL-4 and MIP-1β in Mtg16−/− colons (*p<0.05, **p<0.01, ***p<0.001).