Table 2.

Histomorphometric analysis of bone phenotype when C57BL/6 and Pyk2−/− recipient mice are reconstituted with C57BL/6 or GATA-1 cells.

Recipient Mice	Donor Cells	No. of Mice	BV/TV	N.Ob/T.Ar	N.Oc/T.Ar	N.Ob/BS	Oc.S/BS
C57BL/6	C57BL/6	12	4.4 ± 0.5	42 ± 4	28 ± 3	1.1 ± 0.5	9.9 ± 0.8
C57BL/6	GATA-1	9	6.8 ± 0.9*	66 ± 6*	53 ± 10*	0.8 ± 0.2	13.1 ± 0.9*
Pyk2−/−	C57BL/6	11	6.9 ± 1.2	72 ± 12	41 ± 5	0.9 ± 0.2	11.0 ± 2.3
Pyk2−/−	GATA-1	11	6.0 ± 0.8	71 ± 12	49 ± 8	0.7 ± 0.1	11.3 ± 1.8

BV/TV, bone volume/tissue volume; N.Ob/T.Ar, osteoblast number/tissue area; N.Oc/T.Ar, osteoclast number/tissue area; N.Ob/BS, osteoblast number/bone surface; Oc.S/BS, osteoclast surface/bone surface.

Results are presented as mean ± SEM;

^*p < 0.05 compared with like recipient with C57BL/6 donor cells.